Via which route is vincristine given?

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Multiple Choice

Via which route is vincristine given?

Explanation:
Vincristine must be given by intravenous route. It has very poor and unpredictable oral bioavailability, so taking it by mouth doesn’t deliver reliable systemic exposure. It’s also a vesicant, meaning if it leaks into surrounding tissue from a needle, it can cause severe local tissue necrosis. Therefore other routes such as subcutaneous or intramuscular injections pose a high risk of local damage, and the drug is delivered IV to ensure controlled, safe entry into the bloodstream.

Vincristine must be given by intravenous route. It has very poor and unpredictable oral bioavailability, so taking it by mouth doesn’t deliver reliable systemic exposure. It’s also a vesicant, meaning if it leaks into surrounding tissue from a needle, it can cause severe local tissue necrosis. Therefore other routes such as subcutaneous or intramuscular injections pose a high risk of local damage, and the drug is delivered IV to ensure controlled, safe entry into the bloodstream.

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