The immediate temperature application for a Doxorubicin/Daunorubicin extravasation involves:

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Multiple Choice

The immediate temperature application for a Doxorubicin/Daunorubicin extravasation involves:

Explanation:
Cold application is used because doxorubicin/daunorubicin are vesicant drugs, and the goal right away is to limit tissue damage by slowing the spread of drug into surrounding tissues. Cold causes vasoconstriction, which reduces local blood flow and slows diffusion of the drug, helping to minimize necrosis and inflammation. Warm or hot application would cause vasodilation, increasing blood flow and promoting more rapid spread of the drug, making the injury worse. So, the immediate step is a cold compress to limit damage. If extravasation is suspected, follow protocol for additional interventions as needed.

Cold application is used because doxorubicin/daunorubicin are vesicant drugs, and the goal right away is to limit tissue damage by slowing the spread of drug into surrounding tissues. Cold causes vasoconstriction, which reduces local blood flow and slows diffusion of the drug, helping to minimize necrosis and inflammation. Warm or hot application would cause vasodilation, increasing blood flow and promoting more rapid spread of the drug, making the injury worse. So, the immediate step is a cold compress to limit damage. If extravasation is suspected, follow protocol for additional interventions as needed.

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